I would like to discuss in this time about radiation damage and fucoidan effect.

As you know that radiation therapy is one of the cancer conventional treatment, however radiation will cause quite bit of latent damages. Especially, children will have radiation damage permanently, because radiation damage will be caused cells death, and will affect immune cells as well, particularly radiation will damage on bone marrow according to Janet Helen Fitton in 2011.

The major function of bone marrow is to generate blood cells in which quite important is Hematopoietic stem cells regenerating the immune system in the bone marrow. And bone marrow has two types, red bone marrow and yellow bone marrow. Red bone marrow helps produce blood cells (immune cells) and yellow bone marrow helps store fat (energy source).

Although fucoidan is a chelating agent, it is not recognized as radionuclide removing agent. However based on the research of Byon Y. Y et al., it has been indicated to contribute radiation protection in both in vitro and mouse models.

Byon and his colleagues measured the expression level of cell surface markers in bone marrow stem cells after irradiation. In the study, fucoidan was given in intraperotoneal before irradiation, because bone marrow is the main source of cells of the hematopoietic and immune system. The results suggested that specific cell populations, granulocytes, selectively survive in response to fucoidan treatment after irradiation.

Also According to the research of Rhee K. H. et al in 2011, showed the potential for protection from gamma irradiation in mice and in vitro. The result found that fucoidan was protected against changes in the count of blood cells, and several parameters indicated better recovery after irradiation.

The erythrocyte count in the irradiated controls ranged from 64% to 67% but the fucoidan-treated group increased gradually, ranging from 75% to 80%. The mean number of survival days and the 50-day survival rate in this group was 29 days and 30% at the highest fucoidan dose as compared to 9 days and 0% for the control group.

Above all, I think the evidence from researches indicate that fucoidan protect bone marrow from radiation and expand survival rate from radiation. That is the reason I would recommend using fucoidan when people perform the cancer conventional treatment.