Doxorubicin (DOXO), a chemotherapy medication, treats various cancers, including breast cancer, solid tumors, leukemia, and soft tissue sarcoma. However, the therapeutic value and clinical application of DOXO are limited by both acute and chronic life-threatening cardiotoxicity, including arrhythmias, tachycardia, and even severe congestive heart failure and left ventricular dysfunction. Doxorubicin causes cellular atrophy; its induction […]
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Platelets play a crucial role in tumor metastasis by being recruited and activated by tumor cells, and subsequently binding to circulating tumor cells (CTCs) to facilitate the spread of tumor cells to distant organs. Therefore, nanoparticles that hitchhike to activated platelets are believed to have excellent targeting ability for primary tumors, CTCs, and metastasis to […]
The biliary tract is a general term for the bile duct, gallbladder, and papilla of the duodenum, which are channels for bile. Hence, malignant tumors occurring in these areas are called biliary tract cancer. Additionally, Cholangiocarcinoma is one of the advanced cancer types that appears as a symptom after it blocks the bile duct and […]
Since the Covid 19 pandemic, enhancing the immune system is mainly considered a critical defense system to protect your body from viruses. So in this blog, I would like to discuss one of the means, probiotics, which can be shared to enhance your immunity by fucoidan. Fucoidan, a sulfated polysaccharide in brown algae, contains […]
In the current blog, I will share the research on Fucoidan by Dr. Miyazaki (Kyushu University), one of the leading researchers on Fucoidan in Japan. I would also like to explain the research content on fucoidan immunomodulatory action, one of the essential items. So far, all fucoidan-related studies have reported bioactivities such as anti-cancer activity […]
Gastric ulcer is one of the common diseases in which the mucous membrane of the stomach is ulcerated, and the stomach wall is damaged. When the condition gets worse, the stomach wall may form a hole, leading to even severe health problems. An ulcer is caused by an imbalance in the secretion volume between the […]
Fucoidan is a natural sulfated polysaccharide that is the primary component of slime that covers the surface of brown algae such as mozuku and mekabu. Many studies have been conducted on fucoidan to activate immunity. It is highly anticipated as a natural component that is effective in preventing infectious diseases and cancer. It has been […]
In the United States alone, more than 5 million people are suffering from Alzheimer’s disease. In addition, the number of patients with Alzheimer’s disease and other dementia continues to grow each year as the proportion of the population aged 65 and over increases in the United States. In Alzheimer’s dementia, as the number of nerve […]
Malignant melanoma is one of the skin cancers caused by malignant melanocytes that make skin pigments. Melanoma develops drug resistance quickly and is highly malignant due to abnormalities in multiple proliferative signaling pathways. For example, in a few studies, epidermal growth factor receptor ERBB3 was abnormal in 70% of cases. There are four similar proteins […]
In this blog, I want to share an ovarian cancer testimonial and to show the release of stress during the difficult time of conventional cancer treatment. 2016 July In 2013, I was diagnosed with ovarian cancer; it was declared as stage 1C. I wanted to be well prepared for the upcoming Chemotherapy. I was very […]