Hyperlipidemia, a disease that sees an increase in its number of patients each year, is a growing concern. The adverse effects of this condition are not limited to the diminished quality of life of patients, but it can also pave the way for life-threatening arteriosclerotic ailments such as cerebral and myocardial infarction. Clinical treatment of […]
Author: Molly
Fucoidan, which is a naturally-occurring compound, has been found in various species of brown algae and is currently attracting attention due to its anti-cancer properties. In order to understand Fucoidan’s anti-cancer mechanisms, it’s important to consider the pathways it affects, as well as its structure and bioavailability. Hence, in this blog, I would like to […]
The foundation of atherosclerotic cardiovascular disease (ACVD) comprises a triad of dyslipidemia, inflammation, and thrombosis. High levels of Low-Density Lipoprotein (LDL) contribute to endothelial dysfunction and inflammation, ultimately leading to atherothrombosis, impaired blood flow, and tissue ischemia/necrosis, making it the most serious form of atherosclerosis. Preventative measures are crucial when it comes to cardiovascular diseases, […]
Anaplastic carcinoma of the thyroid is one of the rare form of thyroid cancer and is highly malignant cancer. Anaplastic Thyroid Cancer accounts for approximately 1% of all cases. The studies reveal that papillary and follicular cancers existed for many years. It is noteworthy that they have undergone a sudden change in their nature, leading […]
Advanced glycation end products, highly toxic advanced glycation end products derived from glyceraldehyde (Advanced Glycation End Product-2) and glycolaldehyde (Advanced Glycation End Product-3), are biologically reactive compounds associated with diabetic complications. Uptake of advanced toxic glycation end-products is inhibited by fucoidan, a sulfated polysaccharide. On the other hand, an antagonistic ligand for scavenger receptors, making […]
Fucoidan from brown seaweeds is known to contain multiple human defense functions. It maintains intestine health, which is normalized by the immune system. Fucoidan is the human defense function that is normalizing the intestinal system, making it indispensable for people’s health in these modern times. It also has biological effects of blood coagulation suppression, antitumor, […]
Fucoidan is a sulfated fucose-rich polysaccharide derived from the cell membranes of seaweed species such as Fucus. It is known to have multiple health benefits as revealed in a few recent studies. Also, carcinoma is the most common type of cancer that occurs in the epithelial tissue of the skin. It may also effect the […]
Fucoidan is a polysaccharide isolated from brown algae. It has multiple healing properties, such as antitumor and antioxidant benefits. Although there are many reports on the prebiotic effects of polysaccharides on the host, there are few that relate the results of Fucoidan on biochemical blood indices, gut microbiota, and metabolic function in healthy hosts. The […]
According to the study “The Roles of Autophagy in Cancer” by Chul Won Yun et al., autophagy is an intracellular degradation process. It occurs under stressful conditions, such as organelle damage, abnormal protein presence, and nutrient deprivation. Regulation of autophagy plays a dual role in tumor suppression and advancement in many cancers. In addition, autophagy […]
In previous studies, it has been proven that Fucoidan has antitumor activity. Additionally, Fucoidan effectively inhibits tyrosinase activity through mixed inhibition. In further research, Fucoidan also has shown a positive effect of suppressing metastasis, including suppression of angiogenesis and proliferation in various cancer cells. Apoptosis may help protect cells and avoid death. Cunha demonstrated that […]