The administration of cytostatic agents to chemotherapy in cancer patients has significant side effects, including inhibiting various parts of hematopoiesis. Hence, in this blog, I would like to introduce a study, “Fucoidan and Fucosylated Chondroitin Sulfate Stimulate Hematopoiesis in Cyclophosphamide Induced Mice” by Natalia Anisimova et al. The following study showed the results of fucoidan […]
Author: Molly
Fucoidan is a sulfated polysaccharide extracted from brown algae; according to previous studies, it has been found to have many beneficial physiological effects. For example, it exhibits antioxidant, anti-inflammatory, and anticancer effects. However, the mechanisms of endoplasmic reticulum (ER) stress-mediated fucoidan-induced apoptosis are still unexplored. Therefore, in this blog, I would like to introduce the […]
Cervical cancer is one of the leading causes of cancer-related death in women worldwide. More than 95% of cervical cancers are caused due to an infection by a virus called human papillomavirus (HPV). Among carcinogenic HPVs, HPV types 16 and 18 are said to progress to precancerous lesions and cervical cancer at a high frequency […]
Fucoidan Ameliorates Renal Injury-Related Calcium-Phosphorus Metabolic Disorder and Bone Abnormality
CKD, or Chronic Kidney Disease, is a gradual failure of the kidney’s function over time. Unfortunately, in patients with chronic kidney disease, there is a high risk of bone fracture with a decline in renal function and onset of bone structural abnormalities. In addition, when fractures restrict physical activity, they weaken muscles further. Hence, appropriate […]
A glioma is a tumor of glial cells (glia) that make up the brain. It is classified as benign glioma, which grows slowly. It has a relatively straightforward border with the adjacent normal part and malignant glioma, which multiplies, invades the adjoining region, and has an unclear edge. According to the WHO classification determined by […]
In this blog, I would like to share the study “Fucoidan inhibition of lung cancer in vivo and in vitro: role of the Smurf2-dependent ubiquitin-proteasome pathway in TGFβ receptor degradation” by Hsien-Yeh Hsu et al. There are many significant types of research on fucoidan and cancer. However, this study is conducted for the first time […]
Oligo-Fucoidan extracted from Laminaria japonica is a sulfated polysaccharide with various biological and beneficial influences, such as anti-inflammatory and antitumor effects, and has also been shown to have beneficial health impacts. The molecular mechanisms underlying the therapeutic effects of oligo-fucoidans in cancer patients remain unclear. Therefore, in this blog, I would like to share the […]
The human body has striated muscles and smooth muscles. For example, the muscles of the limbs and heart related to movement are striated (attached to the skeleton), and the muscles of the stomach, esophagus, and internal organs are smooth (observed in internal organs). Hence, a benign tumor that is developed in the smooth muscle is […]
Obesity, including excessive body fat accumulation, is closely associated with the development of cardiovascular disease, insulin resistance (IR), Type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD). Hypertrophic adipocytes also secrete adipokines such as adiponectin, leptin, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6), which are known to alter insulin activity in adipose tissue, liver, and […]
In this article, I would like to share how fucoidan prevents M2 macrophage differentiation and also discuss how fucoidan differentiates M2 through a study. Macrophage infiltration within and around the tumor nest is one of the essential hallmarks during tumor progression. According to Jiuyang Liu et al., “New insights into M1/M2 macrophages: key modulators in […]