Human noroviruses (HuNoVs) are a leading cause of gastroenteritis worldwide, with yearly outbreaks resulting in hundreds of thousands of deaths, making HuNoV infection a significant global health concern. Despite this, a notable and expanding number of reports are emerging, focusing on the various biological effects that Fucoidans from different species are shown to exert. Fucose-containing […]
Author: Molly
In today’s society, an overconsumption of fats, especially the unsaturated trans fats, significantly increases the risk of developing lifestyle diseases such as obesity and dyslipidemia. Meanwhile, interest in the anti-obesity and prebiotic properties of seaweed polysaccharides has been steadily growing. The potential of Saccharina japonica polysaccharides as anti-obesity and prebiotic agents is significant, though the […]
Fucoidan, a sulfated carbohydrate rich in fucose and derived from brown seaweed and echinoderms, demonstrates antiviral properties against viruses including herpes simplex. Fucoidan also exhibits direct antiviral activity against a range of influenza viruses; previous research indicates it blocks viral attachment, entry, and replication. In this blog, I would like to share the following study […]
Patients with chronic kidney disease (CKD) and impaired kidney function often develop mineral and bone disorders. These include metabolic imbalances in calcium, phosphorus, parathyroid hormone, vitamin D, and FGF23, resulting in abnormal bone structure and vascular calcification. Recently, CKD-mineral and bone disorder (CKD-MBD) has become one of the common complications occurring in CKD patients with […]
Fucoidan, a polysaccharide, comes from marine sources. Fucoidan’s diverse biological activities, including lipid-lowering, anti-atherosclerosis, and anticoagulation, have made it increasingly popular in recent years. In this blog, I would like to introduce the study, “Application of fucoidan as a treatment for cardiovascular and cerebrovascular diseases” by Ke Wang et al. This study reveals how fucoidan […]
Diabetes poses a considerable and growing threat to global human health, as its incidence continues to rise internationally, demanding increased attention to prevention and treatment strategies. Although current medications reduce diabetes mortality and morbidity, their adverse health effects are becoming an urgent issue. In contrast, supplementing with polysaccharides provides an effective, side-effect-free approach to managing […]
The strong correlation between high-salt diets, defined as diets with excessive intakes of salt, and the development of a number of serious illnesses, including hypertension, chronic kidney disease, and various autoimmune diseases, is well established in the medical literature. However, the mechanisms underlying HSD-induced inflammation promotion and exacerbation of these diseases have not been fully […]
Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), is a complex, chronic, and multifactorial gastrointestinal disease of unknown origin that is characterized by periods of intestinal inflammation that relapse and remit. Fucoidan, a sulfated polysaccharide derived from brown algae, in contrast, is a recognized anti-inflammatory agent; furthermore, research indicates that fucoidan […]
Fucoidan Protects against Doxorubicin-Induced Cardiotoxicity by Preventing Mitochondrial Dysfunction
Doxorubicin (DOXO), a chemotherapy medication, treats various cancers, including breast cancer, solid tumors, leukemia, and soft tissue sarcoma. However, the therapeutic value and clinical application of DOXO are limited by both acute and chronic life-threatening cardiotoxicity, including arrhythmias, tachycardia, and even severe congestive heart failure and left ventricular dysfunction. Doxorubicin causes cellular atrophy; its induction […]
The anti-aging properties of Sargassum, a brown algae, have been highlighted in recent studies. Sargassum extracts and their derivatives hold great promise in skincare because of their many benefits, including antioxidant, anti-inflammatory, whitening, skin barrier repair, and moisturizing properties. In this blog, I would like to introduce the study, “Potential Beneficial Effects of Sargassum spp. […]