According to various research findings, cancer cells have a heightened ability to absorb glucose for anaerobic glycolysis, which is their preferred mode of energy production. Hence, the search for new inhibitors of cancer cell metabolism is a promising field in anticancer research. The use of 2-deoxy-D-glucose (2-DG), a glucose analog that cannot be metabolized, has […]
Platelets play a crucial role in tumor metastasis by being recruited and activated by tumor cells, and subsequently binding to circulating tumor cells (CTCs) to facilitate the spread of tumor cells to distant organs. Therefore, nanoparticles that hitchhike to activated platelets are believed to have excellent targeting ability for primary tumors, CTCs, and metastasis to […]
The worldwide increase in cancer cases is a substantial impediment to extending how long people live. Over the last few decades, extensive research has been conducted to find ways to conquer this lethal disease. As a result, cancer treatments such as the three major cancer treatments, molecular targeted therapy, and immunotherapy have made significant progress. […]
Ulcerative colitis and Crohn’s disease are among the conditions categorized as inflammatory bowel disease (IBD), which refers to chronic inflammation in the intestines. IBD not only causes gastrointestinal symptoms such as diarrhea and abdominal pain but also affects the entire body, causing stomatitis, joint pain, skin disorders, and more. When considering the long-term outlook, it […]
Intestinal epithelial cells play a crucial role in allowing food to enter the body while also acting as a strong defense against harmful compounds like food and bacterial toxins. However, their barrier function can be compromised when they come into contact with dAGEs, primarily found in food. In this blog, I would like to share […]
Previous studies have confirmed the impact of fucoidan extracted from Sargassum hemiphyllum on various HCC cell types (such as Huh6, Huh7, SK-Hep1, and HepG2) in both in vivo and in vitro settings, but the exact molecular events underlying these effects have yet to be fully understood. So in this blog, I would like to share […]
Intestinal inflammation significantly increases the risk of colorectal cancer development. In addition, gut microbial imbalance and impaired intestinal barrier are key to this inflammatory process. Under normal circumstances, gut microbes maintain a dynamic balance. Disrupting this balance can lead to an increase in harmful bacteria, which can worsen inflammation in the intestines. Repeated cycles of […]
Cistanche tubulosa, shown in Picture 1, as well as Laminaria japonica, have both been documented to possess a range of beneficial properties, including anti-oxidative, anticoagulant, anti-cancer, and anti-inflammatory effects. These candidates show promise in promoting hair growth and effectively treating dandruff and scalp inflammation. In this blog, I am sharing the following study, “Efficacy of […]
Alcoholic liver disease can manifest in individuals who engage in heavy daily alcohol consumption, leading to the accumulation of fat in the liver and subsequent inflammation. Heavy alcohol consumption can result in the development of a life-threatening condition known as severe alcoholic liver disease. If not treated, it can advance to cirrhosis or liver cancer […]
Osteosarcoma primarily impacts adolescents and is a form of bone cancer. The negative outcomes of chemotherapy, surgical complications, and the potential for postoperative osteoporosis all contribute to a poor prognosis and diminished quality of life following treatment. Fucoidan, a type of sulfated polysaccharide found in brown algae, has gained significant interest due to its potential […]